New hope for tough esophageal cancer: targeted drug trial launches
NCT ID NCT07367516
First seen Jun 27, 2026 · Last updated Jul 02, 2026 · Updated 1 time
Summary
This study tests a new drug called TQB6411 in people with advanced esophageal cancer that has worsened after standard treatments. The drug is designed to target and attack cancer cells. The trial has two parts: first to find a safe dose, then to see if it shrinks tumors. About 105 participants will be enrolled.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- TQB6411 (an antibody-drug conjugate targeting EGFR/c-Met)
- What this could lead to
- If successful, this could provide a new treatment option for people with esophageal cancer that has not responded to standard therapies.
- What could go wrong
- This is an early-phase trial with a small number of participants, so the drug may not prove effective or may cause significant side effects. It is not a cure.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Affiliated Hospital of Southwest Medical University
NOT_YET_RECRUITINGLuzhou, Sichuan, 64600, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Anyang Cancer Hospital
NOT_YET_RECRUITINGAnyang, Henan, 455000, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Cancer Hospital Chinese Academy of Medical Sciences
NOT_YET_RECRUITINGBeijing, Beijing Municipality, 100021, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Fujian Cancer Hospital
NOT_YET_RECRUITINGFuzhou, Fujian, 350000, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Gansu Provincial Tumor Hospital
NOT_YET_RECRUITINGLanzhou, Gansu, 730050, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Guangxi Medical University Cancer Hospital
NOT_YET_RECRUITINGNanning, Guangxi, 530021, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Guizhou Provincial People's Hospital
NOT_YET_RECRUITINGGuangxi, Guizhou, 550002, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Harbin Medical University Cancer Hospital
NOT_YET_RECRUITINGHarbin, Heilongjiang, 150000, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hunan Provincial People's Hospital
NOT_YET_RECRUITINGChangsha, Hunan, 410005, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Jiangsu Cancer Hospital
NOT_YET_RECRUITINGNanjing, Jiangsu, 210000, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Jiangsu Provincial Hospital of Traditional Chinese Medicine
NOT_YET_RECRUITINGNanjing, Jiangsu, 210019, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Jilin Cancer Hospital
NOT_YET_RECRUITINGChangchun, Jilin, 130021, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Linyi cancer Hospital
NOT_YET_RECRUITINGLiyi, Shandong, 276034, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Luoyang Central Hospital (Zhengzhou University Affiliated Luoyang Central Hospital)
NOT_YET_RECRUITINGLuoyang, Henan, 471000, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Northern Jiangsu People's Hospital
NOT_YET_RECRUITINGYangzhou, Jiangsu, 225009, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Shanghai Chest Hospital
NOT_YET_RECRUITINGShanghai, Shanghai Municipality, 200030, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Shanxi Bethune Hospital
NOT_YET_RECRUITINGTaiyuan, Shanxi, 030000, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Sichuan Provincial People's Hospital
NOT_YET_RECRUITINGChengdu, Sichuan, 610072, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Sichuan cancer hosipital
NOT_YET_RECRUITINGChengdu, Sichuan, 610040, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The First Affiliated Hospital of Shantou University Medical College
NOT_YET_RECRUITINGShantou, Guangdong, 515000, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The First Affiliated Hospital of Wenzhou Medical University
NOT_YET_RECRUITINGWenzhou, Zhejiang, 325000, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The Second Affiliated Hospital of Air Force Medical University
NOT_YET_RECRUITINGXi’an, Shanxi, 710000, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The Second Affiliated Hospital of Anhui Medical University
NOT_YET_RECRUITINGHefei, Anhui, 230061, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The Second Affiliated Hospital of Zunyi Medical University
NOT_YET_RECRUITINGZunyi, Guizhou, 563006, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The Second People's Hosital of Jiaozuo
NOT_YET_RECRUITINGJiaozuo, Henan, 454001, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The first affiliated hospital of Zhengzhou university
RECRUITINGZhengzhou, Henan, 450000, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The first hospital of jilin university
NOT_YET_RECRUITINGChangchun, Jilin, 130012, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Tianjin Medical University Cancer Institute & Hospital
NOT_YET_RECRUITINGTianjin, Tianjin Municipality, 300000, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Zhengzhou Central Hospital
NOT_YET_RECRUITINGZhengzhou, Henan, 450000, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Zhongshan Hospital Fudan University
NOT_YET_RECRUITINGShanghai, 200032, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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