New asthma shot aims to tame severe attacks

NCT ID NCT06932263

Recruiting now Disease control Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

Summary

This study is testing an investigational medicine called tozorakimab, given as an injection under the skin, for adults whose asthma is not well-controlled even with standard high-dose inhalers. The main goal is to see if different doses of tozorakimab can safely reduce the number of severe asthma flare-ups (exacerbations) people experience over a year. Researchers will compare the effects of the medicine against a placebo (an inactive injection) in about 540 participants.

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Contacts and locations

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Study contacts

Contact

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Locations

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Bakersfield, California, 93301, United States
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Huntington Beach, California, 92647, United States
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La Mesa, California, 91942, United States
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Newport Beach, California, 92663, United States
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San Jose, California, 95117, United States
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Wilmington, Delaware, 19805, United States
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Cutler Bay, Florida, 33189, United States
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Hialeah, Florida, 33012, United States
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Hialeah, Florida, 33015, United States
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WITHDRAWN

Leesburg, Florida, 34748, United States
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Miami, Florida, 33155, United States
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Miami, Florida, 33175, United States
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Orlando, Florida, 32819, United States
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Palmetto Bay, Florida, 33157, United States
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Tampa, Florida, 33607, United States
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Winter Park, Florida, 32789, United States
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Boise, Idaho, 83706, United States
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Indianapolis, Indiana, 46268, United States
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West Des Moines, Iowa, 50266, United States
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Louisville, Kentucky, 40218, United States
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White Marsh, Maryland, 21162, United States
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Farmington Hills, Michigan, 48336, United States
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Warren, Michigan, 48088, United States
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St Louis, Missouri, 63141, United States
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Bellevue, Nebraska, 68123, United States
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Grand Island, Nebraska, 68803, United States
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Omaha, Nebraska, 68134, United States
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Toms River, New Jersey, 08755, United States
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Maspeth, New York, 11378, United States
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Asheville, North Carolina, 28803, United States
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Huntersville, North Carolina, 28078, United States
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Kings Mountain, North Carolina, 28086, United States
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Toledo, Ohio, 43617, United States
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Edmond, Oklahoma, 73034, United States
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Grants Pass, Oregon, 97527, United States
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Medford, Oregon, 97504, United States
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Portland, Oregon, 97202, United States
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DuBois, Pennsylvania, 15801, United States
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Philadelphia, Pennsylvania, 19140, United States
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Smithfield, Pennsylvania, 15478, United States
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Rock Hill, South Carolina, 29732, United States
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Knoxville, Tennessee, 37919, United States
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Austin, Texas, 78759, United States
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Forney, Texas, 75126, United States
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Kingwood, Texas, 77339, United States
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Tyler, Texas, 75708, United States
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Victoria, Texas, 77901, United States
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Roy, Utah, 84067, United States
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Bellingham, Washington, 98225, United States
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Kingwood, West Virginia, 26537, United States
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Milwaukee, Wisconsin, 53228, United States
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CABA, C1425BEN, Argentina
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Ciudad de Buenos Aires, 1128, Argentina
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Ciudad de Buenos Aires, 1425, Argentina
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La Plata, B1900, Argentina
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Mendoza, 5500, Argentina
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Rosario, 2000, Argentina
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San Miguel de Tucumán, 4000, Argentina
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Caxias do Sul, 95070-560, Brazil
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Criciúma, 88811-000, Brazil
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Porto Alegre, 9061-000, Brazil
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Porto Alegre, 91350-200, Brazil
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Salvador, 40050 410, Brazil
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Santo André, 09080-110, Brazil
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São José do Rio Preto, 15090-000, Brazil
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São Paulo, 04014-002, Brazil
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São Paulo, 05403-000, Brazil
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Sorocaba, 18040-425, Brazil
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Curicó, 3341643, Chile
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Quillota, 2260000, Chile
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Santiago, 7500657, Chile
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Santiago, 7501126, Chile
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Santiago, 7750495, Chile
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Temuco, 4810345, Chile
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Viña del Mar, 2540488, Chile
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Baotou, 014010, China
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Changchun, 130021, China
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Chengdu, 610000, China
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Chongqing, 400010, China
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Guangzhou, 510163, China
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Haikou, 570311, China
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Hefei, 230061, China
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Hohhot, 10050, China
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Huizhou, 516001, China
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Qingdao, 266011, China
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Shanghai, 200025, China
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Shanghai, 200065, China
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Shanghai, 201114, China
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Shenzhen, 518020, China
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Wenzhou, 325027, China
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Xuzhou, 221000, China
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Brest, 29200, France
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Créteil, 94010, France
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Lyon, 69317, France
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Marseille, 13015, France
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Pessac, 33604, France
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Strasbourg, 67091, France
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Suresnes, 92150, France
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ACTIVE_NOT_RECRUITING

Athens, 11521, Greece
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Athens, 17562, Greece
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WITHDRAWN

Ioannina, 45500, Greece
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ACTIVE_NOT_RECRUITING

Pátrai, 26500, Greece
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ACTIVE_NOT_RECRUITING

Thessaloniki, 57001, Greece
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ACTIVE_NOT_RECRUITING

Thessaloniki, 57010, Greece
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Balassagyarmat, 2660, Hungary
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Budapest, 1036, Hungary
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Budapest, 1121, Hungary
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Debrecen, 4032, Hungary
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Gödöllő, 2100, Hungary
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Pécs, 7635, Hungary
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Törökbálint, 2045, Hungary
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Belagavi, 590010, India
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Coimbatore, 641028, India
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Dehradun, 248001, India
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Delhi, 110029, India
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Faridabad, 121012, India
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Gūrgaon, 122001, India
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Kochi, 682027, India
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SUSPENDED

Lucknow, 226003, India
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New Delhi, 110005, India
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Vadodara, 391760, India
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Haifa, 3109601, Israel
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Jerusalem, 91120, Israel
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Kfar Saba, 44281, Israel
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Ramat Gan, 52621, Israel
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Catania, 95123, Italy
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Foggia, 71100, Italy
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Genoa, 16132, Italy
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Roma, 00168, Italy
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Fukuoka, 811-1394, Japan
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Ginowan-shi, 901-2214, Japan
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Hiroshima, 730-0013, Japan
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Ishinomaki, 986-8522, Japan
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Kawaguchi-shi, 332-8558, Japan
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Kiyose-shi, 204-8585, Japan
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Kobe, 650-0017, Japan
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Meguro-ku, 152-8902, Japan
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Miura, 238-0111, Japan
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Neyagawa, 572-8551, Japan
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Sapporo, 060-0033, Japan
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Sapporo, 064-0804, Japan
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Takamatsu, 761-8073, Japan
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Ube, 755-8505, Japan
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Yokohama, 232-0024, Japan
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Yokohama, 232-0066, Japan
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Yokohama, 245-8575, Japan
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Lima, 15046, Peru
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Lima, 15082, Peru
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Lima, 15088, Peru
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Lima, LIMA 1, Peru
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Lima, LIMA 21, Peru
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Lima, LIMA 33, Peru
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Iloilo City, 5000, Philippines
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Las Piñas, 1742, Philippines
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Lipa City, 4217, Philippines
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Manadaluyong City, 1552, Philippines
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Quezon City, 1100, Philippines
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Roxas City, 5800, Philippines
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Benoni, 1501, South Africa
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Brackenfell, 7560, South Africa
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Cape Town, 7700, South Africa
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Durban, 4093, South Africa
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eMkhomazi, 4170, South Africa
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Somerset West, 7130, South Africa
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Tygervalley, 7530, South Africa
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Cheongju-si, 28644, South Korea
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Daegu, 42415, South Korea
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Seoul, 03080, South Korea
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Seoul, 03312, South Korea
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Seoul, 03722, South Korea
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Seoul, 05505, South Korea
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Seoul, 06591, South Korea
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Seoul, 08308, South Korea
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Barcelona, 08003, Spain
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Barcelona, 8025, Spain
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Madrid, 28041, Spain
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Málaga, 29010, Spain
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Mérida, 06800, Spain
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Patraix, 46017, Spain
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Santander, 39008, Spain
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Kaohsiung City, 80756, Taiwan
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New Taipei City, 231, Taiwan
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Taichung, 40705, Taiwan
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Taichung, 433004, Taiwan
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Taipei, 10002, Taiwan
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Taipei, 110, Taiwan
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Taipei, 11220, Taiwan
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Taipei, 11696, Taiwan
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Bangkok, 10700, Thailand
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Chanthaburi, 22000, Thailand
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Chiang Rai, 57000, Thailand
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Chon Buri, 20000, Thailand
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Khon Kaen, 40002, Thailand
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Nakhon Sri Thammarat, 80000, Thailand
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Adana, 01330, Turkey (Türkiye)
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Ankara, 06280, Turkey (Türkiye)
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Bursa, 16059, Turkey (Türkiye)
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Gaziantep, 27470, Turkey (Türkiye)
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Istanbul, 34890, Turkey (Türkiye)
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Kayseri, 38039, Turkey (Türkiye)
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Mersin, 33079, Turkey (Türkiye)
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NOT_YET_RECRUITING

Da Nang, 550000, Vietnam
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Haiphong, 180000, Vietnam
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Hanoi, 100000, Vietnam
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Ho Chi Minh City, 10000, Vietnam
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Ho Chi Minh City, 700000, Vietnam
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NOT_YET_RECRUITING

Ho Chi Minh City, 700000, Vietnam
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NOT_YET_RECRUITING

Huế, 530000, Vietnam

Conditions

Explore the condition pages connected to this study.

ASTHMA