New combo therapy aims to rescue breast cancer patients who don't respond to chemo

This study tests a new approach for people with triple-negative breast cancer whose tumors did not shrink after initial chemotherapy. Participants receive a short course of high-precision radiation to the breast tumor, followed by immunotherapy (toripalimab) combined with more chemotherapy. The goal is to see if this combination can eliminate the cancer before surgery and allow more patients to have breast-conserving surgery instead of mastectomy.