New combo attack on aggressive breast cancer shows promise in early trial

NCT ID NCT06682195

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 2 trial is testing whether adding the immunotherapy drug toripalimab to standard chemotherapy before surgery can improve outcomes for women with triple-negative breast cancer. About 35 participants will receive the combination, then undergo surgery. The main goal is to see how many have no cancer cells left in the removed tissue.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Toripalimab (an immunotherapy drug) combined with chemotherapy drugs epirubicin, cyclophosphamide, and albumin-bound paclitaxel

What this could lead to

If successful, this could lead to a more effective treatment approach for triple-negative breast cancer before surgery, potentially improving long-term outcomes.

What could go wrong

This is a small, early-phase trial with only 35 participants and no comparison group. The combination may cause side effects, and results may not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

triple-negative breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Harbin Medical University Cancer Hospital

    NOT_YET_RECRUITING

    Harbin, China

    Contact

  • Jinhua Municipal Central Hospital

    RECRUITING

    Jinhua, China

    Contact

  • Nanchang People's Hospital

    NOT_YET_RECRUITING

    Nanchang, Jiangxi, China

    Contact

  • Nantong First People's Hospital

    RECRUITING

    Nantong, China

    Contact

  • Shanxi Provincial Cancer Hospital

    NOT_YET_RECRUITING

    Shanxi, China

    Contact

  • Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University

    RECRUITING

    Hangzhou, China

    Contact

  • The First Affiliated Hospital of Anhui Medical University

    RECRUITING

    Hefei, China

    Contact

  • The First Affiliated Hospital of Zhejiang University

    RECRUITING

    Hangzhou, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The First Affiliated Hospital of Zhengzhou University

    RECRUITING

    Zhengzhou, China

    Contact

  • The Second Affiliated Hospital of Xi'an Jiaotong University

    NOT_YET_RECRUITING

    Xi'an, China

    Contact

  • Xinjiang Medical University Affiliated Cancer Hospital

    NOT_YET_RECRUITING

    Xinjiang, China

    Contact

  • Zhejiang Cancer Hospital

    RECRUITING

    Hangzhou, China

    Contact

  • Zhongshan Hospital, Fudan University

    RECRUITING

    Shanghai, China

    Contact