Friendly bacteria gel could tame eczema flares

NCT ID NCT06504160

Recruiting now Disease control Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 02, 2026 · Updated 1 time

Summary

This early-stage trial is testing whether a gel containing beneficial bacteria (Staphylococcus hominis A9) can safely control eczema flares. About 86 adults and children aged 6 and older will apply the gel or a placebo twice daily for 14 weeks, along with a short course of steroid cream. The goal is to see if the bacteria help keep eczema under control longer after steroids are stopped.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Staphylococcus hominis A9 (ShA9) bacteria in a topical gel
What this could lead to: If it works, this could offer a new way to manage eczema by using friendly bacteria to prevent flares, reducing the need for steroids.
What could go wrong: This is an early Phase 1 trial with only 86 participants, so results are preliminary. The gel may not work better than placebo, and there could be skin reactions or other side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ATOPIC DERMATITIS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

atopic eczema Eczema

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ATOPIC DERMATITIS

Contacts and locations

Locations

Cincinnati Children's Hospital Medical Center: Asthma Center
RECRUITING

Cincinnati, Ohio, 45229, United States
Icahn School of Medicine at Mount Sinai: Department of Pediatrics Allergy & Immunology
RECRUITING

New York, New York, 10029, United States
National Jewish Health: Division of Pediatric Allergy and Clinical Immunology
RECRUITING

Denver, Colorado, 80206, United States
New York University Langone Health: Department of Pediatric Allergy and Immunology
TERMINATED

New York, New York, 10016, United States
Northwestern University Feinberg School of Medicine: Department of Dermatology
RECRUITING

Chicago, Illinois, 60611, United States
University of California, San Diego: Dermatology Clinical Trials Unit
RECRUITING

San Diego, California, 92093, United States
University of Rochester Medical Center: Department of Dermatology
RECRUITING

Rochester, New York, 10029, United States
University of Wisconsin School of Medicine and Public Health: Division of Pediatric Allergy, Immunology and Rheumatology
RECRUITING

Madison, Wisconsin, 53792, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.