Scientists hunt for genetic clues to stubborn baby and adult teeth

NCT ID NCT07587567

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study aims to understand why some teeth fail to erupt (come in) properly. Researchers will look at dental records and test for changes in the PTH1R gene in 50 patients with eruption problems. The goal is to improve diagnosis and distinguish between different causes, such as ankylosis or genetic failure.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
PTH1R gene analysis
What this could lead to
If successful, this could lead to better ways to diagnose why teeth fail to erupt, helping dentists choose the right treatment sooner.
What could go wrong
This is a small, early-stage study with only 50 people. It is not testing a treatment, so it won't directly help patients yet. Genetic findings may not apply to everyone.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

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