New surgical flap aims to restore swallowing and speech in obese tongue cancer patients

NCT ID NCT07682467

First seen Jul 06, 2026 · Last updated Jul 07, 2026 · Updated 1 time

Summary

This pilot study tests a new surgical technique called the anterolateral thigh myofascial fat composite flap (ALT-MF) for repairing tongue defects after cancer surgery in obese patients (BMI 30 or higher). Traditional flaps can be too bulky in obese patients, leading to problems with swallowing and speech. The study compares ALT-MF with traditional flaps in 35 patients to see if it improves swallowing function and speech clarity after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Anterolateral thigh myofascial fat composite flap (ALT-MF) surgical procedure
What this could lead to
If successful, this technique could offer a better surgical option for obese patients with tongue cancer, improving their ability to swallow and speak after surgery.
What could go wrong
This is a small pilot study with only 35 participants, so results may not apply to all patients. The new flap may not outperform traditional methods and carries standard surgical risks.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Sun Yat-Sen Memorial Hospital

    Guangzhou, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.