New hope for Sjogren's: oral drug safety trial underway

NCT ID NCT04496960

First seen Jan 11, 2026 · Last updated May 19, 2026 · Updated 23 times

Summary

This study tests the safety of tofacitinib, an oral drug, in 23 adults with mild-to-moderate Sjogren's syndrome, an autoimmune disease. Participants take the drug or a placebo for 168 days and undergo various tests like exams, biopsies, and questionnaires. The goal is to see if tofacitinib is safe and tolerable for future use.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States

Conditions

Explore the condition pages connected to this study.