Arthritis drug shows promise against rare childhood brain tumor

NCT ID NCT05233397

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a drug called tocilizumab, already used for arthritis, in children and young adults with a rare brain tumor called adamantinomatous craniopharyngioma that has come back or is growing. The goal is to see if the drug can shrink the tumor or stop it from growing. About 30 participants aged 1 to 39 will receive the drug and be monitored for response.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Children's Hospital Colorado

    RECRUITING

    Aurora, Colorado, 80045, United States

  • Children's National Medical Center

    RECRUITING

    Washington D.C., District of Columbia, 20010, United States

  • Cincinnati Children's Hospital Medical Center

    RECRUITING

    Cincinnati, Ohio, 45229, United States

  • Duke Children's Hospital

    RECRUITING

    Durham, North Carolina, 27710, United States

  • McGill University Health Center

    RECRUITING

    Montreal, Quebec, Canada

  • Nationwide Children's Hospital

    RECRUITING

    Columbus, Ohio, 43235, United States

  • Nicklaus Children's Hospital

    ACTIVE_NOT_RECRUITING

    Miami, Florida, 33155, United States

  • Perth Children's Hospital

    RECRUITING

    Perth, Western Australia, 6000, Australia

  • Queensland Children's Hospital

    RECRUITING

    South Brisbane, Queensland, 4101, Australia

  • Seattle Children's Hospital

    RECRUITING

    Seattle, Washington, 98105, United States

  • Stollery Children's Hospital

    RECRUITING

    Edmonton, Alberta, T6G2B7, Canada

  • Sydney Children's Hospital

    RECRUITING

    Randwick, New South Wales, 2031, Australia

  • Texas Children's Hospital

    RECRUITING

    Houston, Texas, 77030, United States

  • The Hospital for Sick Children (SickKids)

    RECRUITING

    Toronto, Ontario, M5G1X8, Canada

More trials for these conditions

Other studies related to the condition(s) this trial covers.