Arthritis drug shows promise against rare childhood brain tumor

NCT ID NCT05233397

First seen Nov 01, 2025 · Last updated May 12, 2026 · Updated 23 times

Summary

This study tests a drug called tocilizumab, already used for arthritis, in children and young adults (ages 1 to 39) with a rare brain tumor called adamantinomatous craniopharyngioma that has come back or is growing. The goal is to see if the drug can shrink the tumor or stop it from growing. About 30 participants will receive the drug intravenously, and researchers will monitor tumor response and side effects.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Children's Hospital Colorado

    RECRUITING

    Aurora, Colorado, 80045, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Children's National Medical Center

    RECRUITING

    Washington D.C., District of Columbia, 20010, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Cincinnati Children's Hospital Medical Center

    RECRUITING

    Cincinnati, Ohio, 45229, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Duke Children's Hospital

    RECRUITING

    Durham, North Carolina, 27710, United States

    Contact Phone: •••-•••-••••

  • McGill University Health Center

    RECRUITING

    Montreal, Quebec, Canada

    Contact Email: •••••@•••••

  • Nationwide Children's Hospital

    RECRUITING

    Columbus, Ohio, 43235, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Nicklaus Children's Hospital

    ACTIVE_NOT_RECRUITING

    Miami, Florida, 33155, United States

  • Perth Children's Hospital

    RECRUITING

    Perth, Western Australia, 6000, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Queensland Children's Hospital

    RECRUITING

    South Brisbane, Queensland, 4101, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Seattle Children's Hospital

    RECRUITING

    Seattle, Washington, 98105, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Stollery Children's Hospital

    RECRUITING

    Edmonton, Alberta, T6G2B7, Canada

    Contact Email: •••••@•••••

  • Sydney Children's Hospital

    RECRUITING

    Randwick, New South Wales, 2031, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Texas Children's Hospital

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Hospital for Sick Children (SickKids)

    RECRUITING

    Toronto, Ontario, M5G1X8, Canada

    Contact Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.