New hope for kids with rare brain tumor: targeted pill shows promise

NCT ID NCT05286788

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests an oral drug called MEKTOVI (binimetinib) in children and young adults with a rare brain tumor called adamantinomatous craniopharyngioma. The goal is to see if the drug can shrink or control the tumor in patients whose tumor has come back after treatment. About 38 participants aged 1 to 39 will take the drug and be monitored for response and side effects.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

adamantinous craniopharyngioma craniopharyngioma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • British Columbia Children's Hospital

    RECRUITING

    Vancouver, British Columbia, V6H 3N, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU Sainte-Justine

    RECRUITING

    Montreal, Quebec, Canada

    Contact Email: •••••@•••••

  • Children's Hospital Colorado

    RECRUITING

    Aurora, Colorado, 80045, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Children's National Medical Center

    RECRUITING

    Washington D.C., District of Columbia, 20010, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Cincinnati Children's Hospital Medical Center

    RECRUITING

    Cincinnati, Ohio, 45229, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Nationwide Children's Hospital

    RECRUITING

    Columbus, Ohio, 43205, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Nicklaus Children's Hospital

    RECRUITING

    Miami, Florida, 33155, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Perth Children's Hospital

    RECRUITING

    Perth, Western Australia, 6000, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Queensland Children's Hospital

    RECRUITING

    South Brisbane, Queensland, 4101, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Sydney Children's Hospital

    RECRUITING

    Randwick, New South Wales, 2031, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••