New hope for lung cancer: could tobemstomig beat current standard?
NCT ID NCT05775289
First seen Jun 27, 2026 · Last updated Jul 21, 2026 · Updated 2 times
Summary
This study compares a new drug, tobemstomig, combined with chemotherapy against the current standard treatment (pembrolizumab plus chemo) for people with advanced non-small cell lung cancer that has not been treated before. The goal is to see if the new combination works better at delaying cancer growth or shrinking tumors. About 182 participants will take part, and the study is currently active but no longer recruiting.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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?zmir Medical Park
Izm?r, 35575, Turkey (Türkiye)
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AMIISTO Atencion Medica Integral Investigacion y Terapia Oncologica S.A de C.V
Mexico City, Mexico CITY (federal District), 07300, Mexico
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AZ St Maarten Campus Leopoldstr
Mechelen, 2800, Belgium
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AZ.Osp S. Orsola ? Malpighi-Reparto di Oncologia Medica
Bologna, Emilia-Romagna, 40138, Italy
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Ankara City Hospital
Ankara, 06800, Turkey (Türkiye)
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Asan Medical Center
Seoul, 05505, South Korea
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Asst Di Monza
Monza, Lombardy, 20900, Italy
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Azienda Ospedaliera San Giuseppe Moscati
Avellino, Campania, 83100, Italy
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Barwon Health
Geelong, Victoria, 3220, Australia
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CHU de Toulouse - Hôpital Larrey
Toulouse, 31100, France
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Centre Leon Berard
Lyon, 69008, France
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Complejo Hospitalario Universitario A Coruña (CHUAC)
A Coruña, LA Coruna, 15006, Spain
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Crio - Centro Regional Integrado de Oncologia
Fortaleza, Ceará, 60336-550, Brazil
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Henry Ford Health System
Detroit, Michigan, 48202-2689, United States
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Hopital Cochin
Paris, 75679, France
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Hospital Nossa Senhora da Conceicao
Porto Alegre, Rio Grande do Sul, 91350-200, Brazil
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Hospital Regional Universitario Carlos Haya
Málaga, 29011, Spain
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Hospital Son Llatzer
Palma de Mallorca, Balearic Islands, 07198, Spain
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Hospital Universitari Vall d'Hebron
Barcelona, 08035, Spain
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Hospital Universitario 12 de Octubre
Madrid, 28041, Spain
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Hospital de Cancer de Barretos
Barretos, São Paulo, 14784-400, Brazil
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Hospital de Clínicas de Porto Alegre X
Porto Alegre, Rio Grande do Sul, Brazil
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IOV - Istituto Oncologico Veneto - IRCCS
Padova, Veneto, 35128, Italy
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IRCCS AOU San Martino - IST
Genoa, Liguria, 16132, Italy
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Ico Rene Gauducheau
Saint-Herblain, 44805, France
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Institut Catala d Oncologia Hospitalet
L'Hospitalet de Llobregat, Barcelona, 08908, Spain
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Instituto Nacional de Cancerologia
Distrito Federal, 14080, Mexico
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Instituto do Cancer do Estado de Sao Paulo - ICESP
São Paulo, São Paulo, 01246-000, Brazil
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Irccs Istituto Europeo di Oncologia (IEO)
Milan, Lombardy, 20141, Italy
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Jessa Zkh (Campus Virga Jesse)
Hasselt, 3500, Belgium
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Korea University Guro Hospital
Seoul, 08308, South Korea
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Krankenhaus Martha-Maria Halle-Doelau
Halle, 06120, Germany
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LungenClinic Großhansdorf GmbH
Großhansdorf, 22927, Germany
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Lungenfachklinik Immenhausen
Immenhausen, 34376, Germany
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Lyell McEwin Hospital
Adelaide, South Australia, 5112, Australia
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Medipol University Medical Faculty
Istanbul, 34214, Turkey (Türkiye)
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Memorial Ankara Hastanesi
Ankara, 06520, Turkey (Türkiye)
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Monash Health
Melbourne, Victoria, 3168, Australia
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Nucleo de Oncologia da Bahia - NOB
Salvador, Bahia, Estado de Bahia, 40170-380, Brazil
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ONCARE Viaducto Napoles
Mexico City, Mexico CITY (federal District), 03810, Mexico
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Policlinico Universitario "Agostino Gemelli"
Rome, Lazio, 00168, Italy
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Pusan National University Hospital
Busan, 49241, South Korea
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Renown Regional Medical Center Hospital
Reno, Nevada, 89502-1576, United States
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Severance Hospital, Yonsei University Health System
Seoul, 03722, South Korea
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Thoraxklinik Heidelberg gGmbH
Heidelberg, 69126, Germany
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Trakya Universitesi Tip Fakultesi, Medikal Onkoloji Bilim Dali, Balkan Yerleskesi
Edirne, 22030, Turkey (Türkiye)
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UZ Brussel
Brussels, 1090, Belgium
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UZ Leuven Gasthuisberg
Leuven, 3000, Belgium
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Uniklinik Essen
Essen, 45122, Germany
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Westmead Hospital
Westmead, New South Wales, 2145, Australia
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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