Terminated trial tests new drug cocktails for tough cancers

NCT ID NCT04000529

Summary

This early-stage study tested two different drug combinations (TNO155 with either spartalizumab or ribociclib) in adults with advanced solid tumors, including lung, head and neck, and colorectal cancers. The main goal was to find safe doses and understand side effects, not to cure the disease. The study was terminated and involved patients whose cancer had progressed after standard treatments.

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Contacts and locations

Locations

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

  • Novartis Investigative Site

    Westmead, New South Wales, 2145, Australia

  • Novartis Investigative Site

    Brussels, 1200, Belgium

  • Novartis Investigative Site

    Chengdu, Sichuan, 610041, China

  • Novartis Investigative Site

    Cologne, 50937, Germany

  • Novartis Investigative Site

    Hong Kong, Hong Kong

  • Novartis Investigative Site

    Chuo Ku, Tokyo, 104 0045, Japan

  • Novartis Investigative Site

    Singapore, 119228, Singapore

  • Novartis Investigative Site

    Barcelona, Catalonia, 08035, Spain

  • Novartis Investigative Site

    Valencia, Valencia, 46010, Spain

Conditions

Explore the condition pages connected to this study.