Zapping the brain to fight opioid cravings: new study tests TMS

NCT ID NCT07457489

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a non-invasive brain stimulation technique called TMS can reduce cravings and opioid use in people with opioid use disorder. One hundred participants will receive either real or sham TMS sessions over 8 weeks, with follow-up visits for about 5 months. The goal is to see if stimulating a specific brain region can help control cravings and support recovery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Repetitive Transcranial Magnetic Stimulation (rTMS)
What this could lead to
If it works, this could point toward a non-drug treatment to help people with opioid use disorder manage cravings and reduce opioid use.
What could go wrong
This is an early-stage study with no direct benefit to participants. The sham control means some will get no real stimulation, and results may not lead to a proven treatment.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Synaptic Psych

    RECRUITING

    Brentwood, Tennessee, 37027, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Vanderbilt University Medical Center Psychiatric Hospital

    RECRUITING

    Nashville, Tennessee, 37212, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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