Brain zaps may curb meth cravings in small pilot trial

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Diagnosed with an active methamphetamine use disorder * Is engaged in psychosocial treatment or articulates a plan to engage in psychosocial treatment for methamphetamine use disorder during the study period * Age 18 to 60 years * Able to consent for treatment and research participation * English-speaking * Receiving care from UIHC's Addiction Medicine service. This includes patients in the Crisis Stabilization Unit, seen by the inpatient consultation service, enrolling in partial hospitalization or intensive outpatient treatment, or seen in the outpatient Addiction Medicine clinics. Exclusion Criteria: * Age less than 18 years * Patients that are excluded during TMS assessment including: patients with epilepsy or seizure disorder, patients with implanted ferromagnetic equipment in their face or skull near the stimulation target. * Current medical treatment with clozapine or stimulants. * Current diagnosis of bipolar disorder, schizoaffective disorder, schizophrenia, that is deemed by research team psychiatrists not to have been drug-induced. Psychotic disorder not associated with drug use per the MINI International Neuropsychiatric Interview. Psychosis NOS, in remission, or drug-induced psychotic episodes are not exclusion criteria since these may be related to methamphetamine misuse. * Lacks the mental capacity to provide informed consent (i.e. not able to demonstrate understanding of the risks and benefits of participation) * Has a court appointed guardian. * Unstable medical illness. * Current diagnosis of neurological disorder or neurocognitive disorder. * Prior neurosurgical procedure. * History of seizure. * History of ECT treatment within the past three months. * History of any previous TMS treatment. * Known inability to complete the protocol, as assessed by asking them if they are able to make it to all visits for this study without assistance. MRI Exclusion criteria: * Implanted device including pacemaker, coronary stent, defibrillator, or neurostimulation device that is not MRI-compatible * Metal in body including bullets, shrapnel, metal slivers * Claustrophobia * Uncontrolled high blood pressure * Atrial fibrillation * Significant heart disease * Hemodynamic instability * Kidney disease * Pregnant