Scientists use brain implants to watch TMS in action

NCT ID NCT07518745

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study uses special electrodes placed inside the brain to directly measure how transcranial magnetic stimulation (TMS) affects neural activity. Ten adult patients who already have these electrodes for medical reasons will receive single TMS pulses. The goal is to see if TMS can trigger responses in deep brain networks, helping researchers understand brain connectivity and how TMS might be used to treat conditions like depression or epilepsy.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Single pulse transcranial magnetic stimulation (TMS)
What this could lead to
If successful, this could help researchers understand how TMS affects deep brain networks, potentially improving treatments for neurological and psychiatric conditions.
What could go wrong
This is a very small, early-stage study with only 10 participants, focused on measuring brain activity rather than treating a disease. Results may not apply to broader populations.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Pennsylvania

    Philadelphia, Pennsylvania, 19107, United States

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