Jaw pain relief? new injection mix shows promise in small trial
NCT ID NCT07373730
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This completed study tested whether injecting a mix of platelet-rich fibrin and hyaluronic acid into the jaw joint could help people with TMJ disc problems. Thirty adults with jaw pain, clicking, and limited movement received the treatment or a standard injection. Researchers measured changes in mouth opening, jaw movement, pain, and clicking.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- injectable platelet-rich fibrin (I-PRF) mixed with hyaluronic acid
- What this could lead to
- If it works, this could offer a simple injection-based option to reduce jaw pain and improve movement for people with TMJ disorders.
- What could go wrong
- This is a small, early-stage trial with only 30 participants, so results may not apply to everyone. The treatment is not a cure and only aims to ease symptoms.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Faculty of Dentistry, Suez Canal University
Ismailia, Egypt
More trials for these conditions
Other studies related to the condition(s) this trial covers.