Could a simple mineral injection beat standard care for jaw pain?

NCT ID NCT07745660

First seen Aug 04, 2026 · Last updated Aug 05, 2026 · Updated 1 time

Summary

This pilot trial is asking whether injecting magnesium sulfate into the jaw joint after a standard washout procedure (arthrocentesis) can reduce pain and improve jaw function better than the usual treatments. It compares magnesium sulfate against hyaluronic acid (a common injection) and a saline placebo in adults with jaw joint pain or disc displacement. The main focus is on how much chewing pain changes after four weeks, with additional measures of jaw opening, daily function, and quality of life.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
magnesium sulfate
What this could lead to
If magnesium sulfate proves effective, it could offer a new, affordable option for easing jaw pain and improving function after a common TMJ procedure.
What could go wrong
This is a small pilot study, so results may not be definitive. The effect of magnesium sulfate on TMJ pain is not yet established, and individual responses may vary.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Van Yuzuncu Yil University Faculty of Dentistry

    İpekyolu, Van, 65100, Turkey (Türkiye)

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