Engineered immune cells take on Hard-to-Treat lymphoma

NCT ID NCT05989204

First seen Sep 30, 2025 · Last updated May 16, 2026 · Updated 25 times

Summary

This early-phase trial tests a new type of immune cell therapy (TmCD19-IL18 CAR T cells) for people with CD19+ non-Hodgkin lymphoma that has come back or not responded to treatment. The study aims to find the safest dose and check for side effects. About 24 adults will take part at the University of Pennsylvania.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • University of Pennsylvania

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.