Nanotech tooth varnish could beat braces plaque

NCT ID NCT07180849

Recruiting now Disease control Sponsor: Pakistan Institute of Medical Sciences Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares a new fluoride varnish containing titania nanoparticles (made from moringa leaves) with standard fluoride varnish for reducing dental plaque in people with braces. Twenty patients aged 16-30 will receive one of the two varnishes, and researchers will measure plaque levels and bacterial load. The goal is to see if the nanoparticle varnish provides better plaque control.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: titania nanoparticle infused fluoride varnish
What this could lead to: If it works, this could lead to a more effective way to prevent plaque buildup and gum problems for people with braces.
What could go wrong: This is a very small early trial with only 20 participants, so results may not apply to everyone. The new varnish might not work better than the standard one.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DENTAL PLAQUE ACCUMULATION FLUORIDE VARNISHES NANOPARTICLES

Contacts and locations

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Locations

Pakistan Institute of Medical Sciences
RECRUITING

Islamabad, Pakistan

Contact Phone: •••-•••-•••• Email: •••••@•••••

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