Weight-Loss drug tirzepatide tested in kidney transplant patients

NCT ID NCT07423247

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This pilot study tests the safety and effectiveness of tirzepatide (Spartina) for weight loss in 30 obese adults who have had a kidney transplant at least a year ago. Participants receive weekly injections for 24 weeks, with dose adjustments based on tolerance. Researchers will track weight changes, gastrointestinal side effects, and kidney function.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
tirzepatide (Spartina)
What this could lead to
If it works, this could offer a safe way for kidney transplant patients to lose weight and reduce risks like heart disease and graft injury.
What could go wrong
This is a small, early pilot study with only 30 participants and no comparison group. Gastrointestinal side effects and risks to the transplanted kidney are possible.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Nooshin Dalili

    RECRUITING

    Tehran, Iran

    Contact Phone: •••-•••-••••

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