Could a diabetes drug help people with HIV lose weight and fight inflammation?

NCT ID NCT06935838

First seen Oct 31, 2025 · Last updated May 15, 2026 · Updated 29 times

Summary

This study is testing whether tirzepatide, a drug already used for diabetes and weight loss, can help overweight or obese people with well-controlled HIV lose weight and reduce chronic inflammation. Twelve adults will receive weekly injections for 12 weeks, with doses gradually increased. Researchers will track weight, body composition, liver fat, and markers of inflammation and heart health. The goal is to see if this approach can improve overall health in people living with HIV.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • John A Burns School of Medicine

    RECRUITING

    Honolulu, Hawaii, 96813, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.