Could a common blood thinner protect the brain after a burst aneurysm?

NCT ID NCT07493577

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a drug called tirofiban (Aggrastat) in 82 people who have had bleeding from a brain aneurysm. The drug is given through a vein to prevent blood clots that can cause delayed brain damage. The main goal is to find the safest dose, while also checking if it reduces complications like vasospasm and improves recovery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Tirofiban (Aggrastat), a blood-thinning drug given intravenously

What this could lead to

If it works, this could point toward a treatment to reduce delayed brain injury after aneurysm bleeding.

What could go wrong

This is an early, small trial (82 people) focused on safety and dosing. The drug may not improve outcomes and carries bleeding risks.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

acquired aneurysmal subarachnoid hemorrhage subarachnoid hemorrhage

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Duke University Health System

    Durham, North Carolina, 27710, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Texas Health Sciences Center

    Houston, Texas, 77030, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••