New combo therapy may stop stroke from getting worse

NCT ID NCT05310968

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tested whether adding a fast-acting blood thinner (tirofiban) to standard aspirin can prevent strokes from getting worse in people with small artery blockages in the brain. About 970 adults aged 18-80 who had a mild stroke within the last 48 hours took part. The goal was to see if the combination reduces the risk of another stroke or early worsening of symptoms.

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Conditions

The condition(s) this trial relates to.

atherosclerosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Affiliated Nantong Hospital of Shanghai University (The Sixth People's Hospital of Nantong)

    Nantong, Jiangsu, China

  • Baotou Central Hospital

    Baotou, Inner Mongolia, China

  • Benxi Central Hospital

    Benxi, Liaoning, China

  • Changzhi People's Hospital

    Changzhi, Shanxi, China

  • China-Japan Union Hospital of Jilin University

    Changchun, Jilin, China

  • Guanxian People's Hospital

    Liaocheng, Shandong, China

  • Guizhou Provincial People's Hospital

    Guiyang, Guizhou, China

  • Hejian People's Hospital

    Hejian, Hebei, China

  • Jincheng People's Hospital

    Jincheng, Shanxi, China

  • Jiyuan Hospital of Traditional Chinese Medicine

    Jiyuan, Henan, China

  • Liaocheng Central Hospital

    Liaocheng, Shandong, China

  • Mengzhou People's Hospital

    Henan, Henan, China

  • Ningjin People's Hospital

    Dezhou, Shandong, China

  • School of Medicine, Xiamen University

    Zhangzhou, Fujian, China

  • Shandong Provincial Hospital Affiliated to Shandong First Medical University

    Jinan, Shandong, China

  • Shaodong People's Hospital

    Shaoyang, Hunan, China

  • Suixian Hospital of Traditional Chinese Medicine

    Shangqiu, Henan, China

  • Tanghe County People's Hospital

    Nanyang, Henan, China

  • Tangshan Gongren Hospital

    Tangshan, Hebei, China

  • The Affiliated Hospital of Qingdao University

    Qingdao, Shandong, China

  • The Affiliated Shuyang Hospital of Xuzhou Medical University

    Suqian, Jiangsu, China

  • The First Affiliate Hospital of Baotou Medical College

    Baotou, Inner Mongolia, China

  • The First Hospital of Fangshan District Beijing

    Beijing, Beijing Municipality, China

  • The First People's Hospital of Nanyang

    Nanyang, Henan, China

  • The First People's Hospital of Xianyang

    Xianyang, Shaanxi, China

  • The People's Hospital of Biyang County

    Zhumadian, Henan, China

  • The People's Hospital of Gaotang County

    Liaocheng, Shandong, China

  • The People's Hospital of Linqing

    Linqing, Shandong, China

  • The People's Hospital of Qinghe County

    Xingtai, Hebei, China

  • The People's Hospital of Suxitong Science & Technology Inductrial Park

    Nantong, Jiangsu, China

  • The Second Affiliated Hospital of Henan University of Science and Technology

    Luoyang, Henan, China

  • The Second People's Hospital of Liaocheng

    Liaocheng, Shandong, China

  • The Third People's Hospital of Liaocheng

    Liaocheng, Shandong, China

  • Wanrong County People's Hospital

    Yuncheng, Shanxi, China

  • Weihai Wendeng District People's Hospital

    Weihai, Shandong, China

  • Xiuwu People's Hospital

    Jiaozuo, Henan, China

  • Zibo Municipal Hospital

    Zibo, Shandong, China