Could a liver drug protect the brain after a bleeding stroke?
NCT ID NCT01095731
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether tiopronin, a drug used for liver disease, can lower a harmful chemical in the brain and improve recovery after a bleeding stroke from a burst aneurysm. Sixty patients received either tiopronin or a placebo for up to 14 days. The goal was to see if the drug is safe and reduces brain damage.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
tiopronin
What this could lead to
If it works, this could point toward a treatment that reduces brain damage after a bleeding stroke.
What could go wrong
This is an early phase 2 trial with only 60 participants, so results may not apply to everyone. The drug may not improve recovery or could cause side effects.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for ANEURYSMAL SUBARACHNOID HEMORRHAGE are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Columbia University Medical Center
New York, New York, 10032, United States
-
University of Florida
Gainesville, Florida, 32611, United States
-
University of Washington
Seattle, Washington, 96104, United States