New combo therapy shows promise for Hard-to-Treat breast cancer

NCT ID NCT07498478

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether adding tinengotinib to fulvestrant can shrink tumors in people with a common type of advanced breast cancer (HR+/HER2-). About 94 adults whose cancer has returned or spread despite prior treatments will take part. The goal is to find the best dose and see if the combination works better than tinengotinib alone, while monitoring side effects.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm hormone receptor-positive breast cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Beijing Cancer Hospital

    NOT_YET_RECRUITING

    Beijing, China

    Contact

  • Cancer Hospital, Chinese Academy of Medical Sciences

    RECRUITING

    Beijing, 100021, China

    Contact

  • Fudan University Shanghai Cancer Center

    NOT_YET_RECRUITING

    Shanghai, China

    Contact

  • Guangdong Provincial People's Hospital

    NOT_YET_RECRUITING

    Guangzhou, Guangdong, China

    Contact

  • Hunan Cancer Hospital

    NOT_YET_RECRUITING

    Changsha, Hunan, China

    Contact

  • Jiangsu Province Hospital

    NOT_YET_RECRUITING

    Nanjing, Jiangsu, China

    Contact

  • Linyi Cancer Hospital

    RECRUITING

    Linyi, Shandong, China

    Contact

  • Shandong Cancer Hospital

    NOT_YET_RECRUITING

    Jinan, Shandong, China

    Contact

  • Southwest Hospital

    NOT_YET_RECRUITING

    Chongqing, China

    Contact

  • The First Medical Center, Chinese PLA General Hospital

    NOT_YET_RECRUITING

    Beijing, China

    Contact

  • Tianjin Medical University Cancer Institute & Hospital

    NOT_YET_RECRUITING

    Tianjin, China

    Contact

  • Zhejiang Cancer Hospital

    NOT_YET_RECRUITING

    Hangzhou, Zhejiang, China

    Contact

  • Zhongnan Hospital of Wuhan University

    NOT_YET_RECRUITING

    Wuhan, Hubei, China

    Contact