Body clock check: a simple swab may guide immunotherapy timing for lung cancer

This study explores whether a hair follicle or cheek swab can accurately measure a person's internal body clock (circadian rhythm) in patients with advanced lung cancer receiving immunotherapy. Researchers will use a new tool called TimeTeller to analyze gene activity from these samples. The goal is to see if different chronotypes (early birds vs. night owls) respond better to immunotherapy and whether treatment itself alters the body clock. This is an observational study, meaning no new treatment is given—just monitoring and sample collection.