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Thyroid surgery under the microscope: what 3,000 real operations reveal

NCT ID NCT07812779

Knowledge-focused Sponsor: Pirogov Russian National Research Medical University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 10, 2026 · Last updated Sep 11, 2026 · Updated 1 time

Summary

Researchers at a Moscow medical center are studying the quality and outcomes of thyroid surgery using real-world clinical data. The study follows patients who had thyroid operations for benign or malignant disease, tracking complications, cancer results, and long-term outcomes. By analyzing routine care data from thousands of operations, the team aims to understand how well thyroid surgery works in everyday practice and how reliable such data is for research.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If the study identifies which surgical approaches and care patterns lead to fewer complications, it could help surgeons and hospitals refine thyroid surgery practices and improve patient outcomes.
What could go wrong
This is an observational study, so it can show associations but cannot prove cause and effect. Findings from one center may not apply to other hospitals or patient populations.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 3,000 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Sep 2026

An estimate. Start dates often move.

Expected to finish

Jan 2032

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients treated surgically for benign or malignant thyroid disease at a single multidisciplinary medical center in Moscow. The population is identified from routine clinical-care data and includes historical patients as well as newly accrued eligible patients. Primary, completion, and repeat thyroid operations are eligible when the relevant data can be linked and the episode meets the specific substudy requirements.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patient undergoes or previously underwent an operation involving the thyroid gland at the study institution during the study period. * The operation was performed for a benign or malignant thyroid disease, including primary, completion, or repeat thyroid surgery. * Source data permit linkage of the patient, hospitalization, operation, and index date. * For a specific substudy, the participant/episode meets the additional prespecified requirements for the relevant exposure and outcome. Exclusion Criteria: \- Procedure predominantly involving the parathyroid glands without a confirmed relationship to thyroid disease. * Procedure or record without a confirmed relationship to thyroid disease. * Technical duplicate record. * Episode for which the essential temporal sequence or index date cannot be established for the relevant analysis. * Record lacking the minimum data required to determine the primary outcome of the specific substudy.

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Conditions

The condition(s) this trial relates to.

adrenal gland cancer adrenal gland neoplasm Carcinoma, Medullary familial medullary thyroid carcinoma goiter Postoperative Complications thyroid cancer thyroid gland disorder Thyroid Neoplasms Thyroid Nodule thyroid tumor

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Adrenal cancer Adrenal gland neoplasms Endocrine surgery Goiter Medullary thyroid carcinoma Neck dissection Real-world data Thyroid cancer Thyroid diseases Thyroid neoplasms Thyroid nodules Thyroid surgery for benign disease

How to take part

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  1. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  2. A doctor treating you

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