Could a thyroid boost help tiny preemies grow smarter and stronger?

NCT ID NCT07625722

Not yet recruiting Disease control Sponsor: Shandong Provincial Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This trial investigates whether giving a thyroid hormone (levothyroxine) to very small preterm infants with mildly low thyroid function can improve their physical growth and brain development by age two. The study includes infants born weighing under 1500 grams who are small for their gestational age. Researchers will compare those who receive the hormone with those who do not, tracking height, weight, head size, and thinking skills.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: levothyroxine (thyroid hormone)
What this could lead to: If it works, this could point toward a simple treatment to improve growth and brain development in vulnerable preterm infants.
What could go wrong: This is a small, early-stage trial, so results may not apply broadly. The hormone dose must be carefully adjusted to avoid side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for NEURODEVELOPMENT OUTCOME are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

fetal growth restriction neurodevelopmental disorder Premature Birth

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

NEURODEVELOPMENT OUTCOME PRETERM SGA AND GROWTH THYROID FUNCTION

Contacts and locations

Locations

Shandong Provincial Hospital Affiliated to Shandong First Medical University

Jinan, Shandong, 250021, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.