New hope for breast cancer patients with brain tumors: drug combo enters trial

NCT ID NCT07152782

First seen Nov 01, 2025 · Last updated May 13, 2026 · Updated 32 times

Summary

This phase 2 trial tests whether adding neratinib to the standard drug trastuzumab deruxtecan helps control HER2-positive breast cancer that has spread to the brain. About 202 women aged 18-70 will be randomly assigned to one of two treatment groups. The goal is to see if the combination slows cancer growth better than the single drug alone.

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Contacts and locations

Study contacts

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Conditions

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