New drug duo aims to slash myeloma relapse after transplant

NCT ID NCT07542418

First seen Apr 25, 2026 · Last updated Jun 18, 2026 · Updated 9 times

Summary

This study tests whether adding thiotepa to the standard melphalan treatment before a stem cell transplant can lower the chance of multiple myeloma coming back within a year. It includes 204 adults aged 18-70 whose cancer was not fully cleared by prior therapy. Participants are randomly assigned to get either the new two-drug combo or melphalan alone, then receive their own stem cells and are followed for one year.

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