New drug combo aims to cut relapse in multiple myeloma transplant patients

NCT ID NCT07542418

First seen Apr 25, 2026 · Last updated Jun 10, 2026 · Updated 8 times

Summary

This study tests whether adding thiotepa to the standard chemotherapy (melphalan) before a stem cell transplant can lower the chance of cancer returning in people with multiple myeloma. It includes 204 adults aged 18-70 who did not achieve complete remission before transplant. Participants are randomly assigned to receive either the new combo or standard treatment, and are followed for one year to track relapse and side effects.

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