Breakthrough study turns hepatitis c kidneys into lifesaving transplants

NCT ID NCT04075916

First seen Nov 01, 2025 · Last updated Apr 29, 2026 · Updated 23 times

Summary

This study tested whether kidneys from donors with hepatitis C can be safely transplanted into people without the virus. After transplant, patients received antiviral medication to cure the hepatitis C infection. The goal was to expand the number of available kidneys for people with end-stage kidney disease. The trial included 201 adult kidney transplant candidates and compared their outcomes to those who received kidneys from non-infected donors.

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Contacts and locations

Locations

  • Cleveland Clinic

    Cleveland, Ohio, 44195, United States

  • Hospital of the University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

  • Jackson Memorial Hospital/University of Miami

    Miami, Florida, 33136, United States

  • Johns Hopkins

    Baltimore, Maryland, 21287, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

  • Medical University of South Carolina

    Charleston, South Carolina, 29425, United States

  • New York Presbyterian Hospital/Columbia University

    New York, New York, 10032, United States

  • University of Alabama at Birmingham

    Birmingham, Alabama, 35294, United States

  • University of Cincinnati

    Cincinnati, Ohio, 45267, United States

  • University of Florida

    Gainesville, Florida, 32608, United States

  • Vanderbilt University

    Nashville, Tennessee, 37235, United States

Conditions

Explore the condition pages connected to this study.