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Magnetic brain zaps could replace antidepressants for some patients

NCT ID NCT05732298

Ongoing Symptom relief Sponsor: University of Regensburg Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a non-invasive brain stimulation method called theta burst stimulation can help people with depression who refuse medication. 72 participants will either start treatment right away or wait four weeks. The goal is to see if the stimulation alone can reduce depression symptoms.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
theta burst stimulation (a type of transcranial magnetic stimulation)
What this could lead to
If it works, this could offer a drug-free option for people with depression who cannot or will not take antidepressants.
What could go wrong
This is a small, early-stage trial with only 72 participants. The treatment is not yet proven, and results may not apply to everyone with depression.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Depression depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DEPRESSION

Contacts and locations

Locations

  • Department of Psychiatry and Psychotherapy

    Regensburg, 93053, Germany

More trials for these conditions

Other studies related to the condition(s) this trial covers.