Cannabis compound tested as a way to soften painful memories

This early-phase trial investigates whether delta-9-tetrahydrocannabinol (THC), the main psychoactive compound in cannabis, can reduce the emotional and physical responses triggered by recalling stressful experiences. Healthy adults aged 18–35 with some prior cannabis use will receive either a low or moderate dose of THC or a placebo before being exposed to cues linked to a stressful memory. Researchers will measure self-reported distress and heart-related responses to see if THC dampens the reaction, both immediately and one week later.