Drug cocktail may cut transfusions for thalassemia patients

NCT ID NCT07292259

First seen Jan 07, 2026 · Last updated May 11, 2026 · Updated 17 times

Summary

This study tested whether a combination of two drugs, thalidomide and hydroxyurea, can reduce the need for blood transfusions in people with transfusion-dependent beta thalassemia. 100 patients aged 2 years and older took the drugs for one year. The main goal was to see if the number of transfusions decreased. The study also tracked side effects. This approach aims to control the disease, not cure it.

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Contacts and locations

Locations

  • AFBMTC (CT&RC), CMH Medical Complex

    Rawalpindi, Punjab Province, 46000, Pakistan

  • AFBMTC (CT&RC), Medical Complex

    Rawalpindi, Punjab Province, 46000, Pakistan

  • AFBMTC (Clinical Trial and Research Cell)

    Rawalpindi, Punjab Province, 46000, Pakistan

  • AFBMTC, CMH Medical Complex

    Rawalpindi, Punjab Province, 46000, Pakistan

  • Armed Forces Bone Marrow Transplant Center

    Islamabad, Punjab Province, 46000, Pakistan

  • Armed Forces Bone Marrow Transplant Center

    Rawalpindi, Punjab Province, 44000, Pakistan

  • Armed Forces Bone Marrow Transplant Center

    Rawalpindi, Punjab Province, 46000, Pakistan

  • Armed Forces Bone Marrow Transplant Center Rawalpindi Pakistan

    Rawalpindi, Punjab Province, 46000, Pakistan

  • Armed Forces Bone Marrow Transplant Center Rawalpindi Pakistan

    Rawalpindi, Punjab Province, 60000, Pakistan

Conditions

Explore the condition pages connected to this study.