Old drug, new hope: thalidomide tested for Kids' fever disorder
NCT ID NCT07476625
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether thalidomide can reduce or stop fever episodes in children with PFAPA syndrome, a condition causing repeated fevers and sore throats. About 106 children aged 3 to 18 will take either thalidomide or colchicine daily for 6 months. Researchers will track how many children have no fevers during treatment and monitor for side effects.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
thalidomide
What this could lead to
If it works, this could offer a new treatment option to control fever episodes in children with PFAPA syndrome.
What could go wrong
This is an early-stage trial with only 106 participants, so results may not apply to all children. Thalidomide has known side effects, including drowsiness and nerve damage.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
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