New hope for kids with rare cancer: thalidomide combo shows promise

NCT ID NCT06470464

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 22 times

Summary

This study tested a new treatment for children with a rare type of cancer called yolk sac tumor that had come back or stopped responding to standard chemotherapy. The treatment combined the drug thalidomide with three chemotherapy drugs. The goal was to see if this combination could shrink or control the tumors. The study included 20 children and measured how many had a significant reduction in tumor size or a drop in a key tumor marker.

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Contacts and locations

Locations

  • Shandong Cancer Hospital and Institute

    Jinan, Shandong, 250117, China

Conditions

Explore the condition pages connected to this study.