Scientists hunt for clues to predict when lung fluid dries up
NCT ID NCT02092155
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tracks 95 people with cancer-related fluid buildup around the lung who have a tunneled pleural catheter. Researchers measure a protein called TGF-B in the fluid to see if it can predict when the fluid stops draining on its own (pleurodesis). The goal is to understand who will achieve pleurodesis and how it happens, which could guide future care.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this could help doctors predict which patients will naturally stop needing their pleural catheter, potentially reducing unnecessary procedures.
- What could go wrong
- This is an observational study with no treatment being tested, so it won't directly improve outcomes. The findings may not apply to all patients with malignant pleural effusions.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Johns Hopkins University
Baltimore, Maryland, 21287, United States
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Other studies related to the condition(s) this trial covers.