Scientists hunt for clues to predict when lung fluid dries up

NCT ID NCT02092155

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tracks 95 people with cancer-related fluid buildup around the lung who have a tunneled pleural catheter. Researchers measure a protein called TGF-B in the fluid to see if it can predict when the fluid stops draining on its own (pleurodesis). The goal is to understand who will achieve pleurodesis and how it happens, which could guide future care.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could help doctors predict which patients will naturally stop needing their pleural catheter, potentially reducing unnecessary procedures.

What could go wrong

This is an observational study with no treatment being tested, so it won't directly improve outcomes. The findings may not apply to all patients with malignant pleural effusions.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for MALIGNANT PLEURAL EFFUSIONS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Pleural Effusion, Malignant

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Johns Hopkins University

    Baltimore, Maryland, 21287, United States