Breakthrough drug helps severe asthma patients ditch harmful steroids

NCT ID NCT05274815

Completed Disease control Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

Summary

This study tested whether a drug called tezepelumab, given as a shot, could help adults with severe asthma safely reduce or stop their daily oral steroid pills. It involved 305 participants who were already taking high doses of inhaled medicine plus daily steroid pills. The main goal was to see if people could lower their steroid dose or stop it completely without their asthma getting worse over one year.

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Contacts and locations

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Locations

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Newport Beach, California, 92663, United States
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Newark, Delaware, 19713, United States
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Loxahatchee Groves, Florida, 33470, United States
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Ann Arbor, Michigan, 48109, United States
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Toms River, New Jersey, 08755, United States
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The Bronx, New York, 10467, United States
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DuBois, Pennsylvania, 15801, United States
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Buenos Aires, C1121ABE, Argentina
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CABA, 1426, Argentina
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CABA, C1012AAR, Argentina
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Mendoza, M5500GHB, Argentina
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Monte Grande, 1842, Argentina
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Pilar, 1629, Argentina
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Quilmes, B1878FNR, Argentina
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Ranelagh, 1886, Argentina
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Rosario, 2000, Argentina
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San Fernando, B1646EBJ, Argentina
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San Juan Bautista, 1888, Argentina
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San Miguel de Tucumán, 4000, Argentina
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Brussels (Woluwé-St-Lambert), 1200, Belgium
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Erpent, 5101, Belgium
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Ghent, 9000, Belgium
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Liège, 4000, Belgium
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Haskovo, 6305, Bulgaria
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Razgrad, 7200, Bulgaria
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Sofia, 1142, Bulgaria
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Sofia, 1431, Bulgaria
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Sofia, 5000, Bulgaria
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Velika Tarnovo, 5250, Bulgaria
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Antony, 92160, France
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Bordeaux, 33076, France
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Brest, 29609, France
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Lyon, 69004, France
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Marseille, 13915, France
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Montpellier, France
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Nantes, 44000, France
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Nice, 06000, France
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Berlin, 12203, Germany
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Darmstadt, 64283, Germany
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Fürstenwalde, 15517, Germany
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Mainz, 55128, Germany
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Reinfeld (Holstein), 23858, Germany
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Daugavpils, LV-5410, Latvia
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Daugavpils, LV-5417, Latvia
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Jūrmala, LV-2015, Latvia
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Riga, LV-1011, Latvia
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Riga, LV1002, Latvia
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Riga, LV1010, Latvia
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Valmiera, LV-4201, Latvia
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Chihuahua City, 31000, Mexico
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Chihuahua City, 31200, Mexico
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Guadalajara, 44100, Mexico
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Monterrey, 64360, Mexico
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Bychawa, 23100, Poland
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Chmielnik, 26-020, Poland
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Gdansk, 80-952, Poland
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Krakow, 31-011, Poland
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Lodz, 92-213, Poland
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Ostrowiec Świętokrzyski, 27-400, Poland
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Sosnowiec, 41-200, Poland
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Wroclaw, 50-044, Poland
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Wroclaw, 53-301, Poland
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Wroclaw, 54-239, Poland
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Badalona, 08916, Spain
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Barcelona, 8035, Spain
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Madrid, 28041, Spain
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Oviedo, 33011, Spain
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Santa Cruz de Tenerife, 38010, Spain
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Santander, 39008, Spain
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Seville, 41009, Spain
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Belfast, BT97AB, United Kingdom
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Bradford, BD9 6RJ, United Kingdom
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LE3 9QP, United Kingdom
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London, SE1 7EH, United Kingdom
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London, SW3 6HP, United Kingdom
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Nottingham, NG5 1PB, United Kingdom
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Portsmouth, PO6 3LY, United Kingdom

Conditions

Explore the condition pages connected to this study.

ASTHMA