New drug aims to unblock noses and reduce sinus misery for polyp sufferers

NCT ID NCT06706817

Recruiting now Symptom relief Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 30 times

Summary

This study tests a drug called tezepelumab in 180 adults with chronic sinusitis and nasal polyps who are eligible for surgery. The goal is to see if the drug can reduce nasal congestion and other sinus symptoms over 24 weeks. Participants receive the drug every 4 weeks and report their symptoms using diaries and questionnaires.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

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Newport Beach, California, 92663, United States
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Chicago, Illinois, 60611, United States
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Chestnut Hill, Massachusetts, 02467, United States
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Columbia, Missouri, 65201, United States
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Plovdiv, 4003, Bulgaria
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Sofia, 1431, Bulgaria
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Sofia, 1606, Bulgaria
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Sofia, 1606, Bulgaria
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Hamilton, Ontario, L8S 1G5, Canada
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Québec, Quebec, G1L 3L5, Canada
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Québec, Quebec, G1V 4W2, Canada
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Le Kremlin-Bicêtre, 94270, France
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Lille, 59000, France
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Marseille, 13005, France
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Nantes, 44093, France
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Pierre-Bénite, 69495, France
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Poitiers, 86000, France
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Toulouse, 31400, France
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Düsseldorf, 40225, Germany
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Marburg, 35043, Germany
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Tübingen, 72076, Germany
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Villingen-Schwenningen, 78052, Germany
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Wiesbaden, 65183, Germany
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Budapest, 1085, Hungary
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Budapest, 1134, Hungary
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Nyíregyháza, 4400, Hungary
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Pécs, 7621, Hungary
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Bologna, 40139, Italy
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Catania, 95123, Italy
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Florence, 50139, Italy
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Naples, 80131, Italy
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Padua, 35128, Italy
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Pisa, 56126, Italy
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Roma, 00168, Italy
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Rozzano, 20089, Italy
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Bialystok, 15-879, Poland
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Bydgoszcz, 85-231, Poland
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Lodz, 90-302, Poland
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Zawadzkie, 47-120, Poland
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Barcelona, 08003, Spain
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Barcelona, 08035, Spain
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Cadiz, 11011, Spain
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Madrid, 28041, Spain
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Salamanca, 37007, Spain
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Santiago de Compostela, 15706, Spain

Conditions

Explore the condition pages connected to this study.

CHRONIC RHINOSINUSITIS WITH NASAL POLYPS