New monthly shot aims to tame debilitating COPD attacks

NCT ID NCT06878261

Recruiting now Disease control Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

Summary

This study is testing if a monthly injection called tezepelumab can help adults with moderate to very severe COPD. The main goal is to see if it reduces the number of times a person's breathing suddenly gets much worse (called an exacerbation or flare-up). About 990 participants will receive either the drug or a placebo (dummy injection) for up to 76 weeks to compare results.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

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Cullman, Alabama, 35055, United States
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Phoenix, Arizona, 85044, United States
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Scottsdale, Arizona, 85258, United States
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WITHDRAWN

Inglewood, California, 90301, United States
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Los Angeles, California, 90048, United States
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Palo Alto, California, 94304, United States
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Redding, California, 96001, United States
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San Diego, California, 92108, United States
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New Britain, Connecticut, 06051, United States
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Wilmington, Delaware, 19803, United States
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Bay Pines, Florida, 33744, United States
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Boynton Beach, Florida, 33435, United States
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Clearwater, Florida, 33765, United States
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Fleming Island, Florida, 32003, United States
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Jacksonville, Florida, 32209, United States
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Leesburg, Florida, 34748, United States
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WITHDRAWN

Margate, Florida, 33063, United States
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Miami, Florida, 33126, United States
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Miami, Florida, 33155, United States
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SUSPENDED

Miami Lakes, Florida, 33014, United States
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Ocala, Florida, 34470, United States
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Palmetto Bay, Florida, 33157, United States
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Winter Park, Florida, 32789, United States
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Adairsville, Georgia, 30103, United States
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Atlanta, Georgia, 30349, United States
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Cordele, Georgia, 31015, United States
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NOT_YET_RECRUITING

Decatur, Georgia, 30033, United States
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WITHDRAWN

Fort Eisenhower, Georgia, 30905, United States
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Savannah, Georgia, 31406, United States
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NOT_YET_RECRUITING

Evanston, Illinois, 60201, United States
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Evansville, Indiana, 47725, United States
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Indianapolis, Indiana, 46202, United States
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Indianapolis, Indiana, 46268, United States
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Kansas City, Kansas, 66160, United States
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Bowling Green, Kentucky, 42101, United States
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Owensboro, Kentucky, 42301, United States
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Baltimore, Maryland, 21224, United States
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Potomac, Maryland, 20854, United States
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Ann Arbor, Michigan, 48109, United States
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Minneapolis, Minnesota, 55425, United States
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Hannibal, Missouri, 63401, United States
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NOT_YET_RECRUITING

Staten Island, New York, 10309, United States
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NOT_YET_RECRUITING

Syracuse, New York, 13203, United States
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Charlotte, North Carolina, 28277, United States
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WITHDRAWN

Fayetteville, North Carolina, 28303, United States
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Oklahoma City, Oklahoma, 73102, United States
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Tulsa, Oklahoma, 74133, United States
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Grants Pass, Oregon, 97527, United States
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NOT_YET_RECRUITING

Sayre, Pennsylvania, 18840, United States
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Anderson, South Carolina, 29621, United States
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Columbia, South Carolina, 29204, United States
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Gaffney, South Carolina, 29340, United States
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Spartanburg, South Carolina, 29303, United States
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Union, South Carolina, 29379, United States
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Rapid City, South Dakota, 57702, United States
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Knoxville, Tennessee, 37919, United States
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Boerne, Texas, 78006, United States
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El Paso, Texas, 79902, United States
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Houston, Texas, 77008, United States
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Houston, Texas, 77074, United States
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NOT_YET_RECRUITING

Houston, Texas, 77094, United States
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Lewisville, Texas, 75067, United States
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McKinney, Texas, 75069, United States
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Mesquite, Texas, 75149, United States
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NOT_YET_RECRUITING

San Antonio, Texas, 78258, United States
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Colchester, Vermont, 05446, United States
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Williamsburg, Virginia, 23188, United States
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Everett, Washington, 98208, United States
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Alberdi, X5033DCE, Argentina
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Buenos Aires, C1425BEN, Argentina
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Ciudad de Buenos Aires, C1414AIF, Argentina
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Florida, B1602DQD, Argentina
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La Plata, B1900, Argentina
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La Plata, B1904, Argentina
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Mar del Plata, 7600, Argentina
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Mendoza, M5500CCG, Argentina
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Quilmes, B1878FNR, Argentina
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Rosario, 2000, Argentina
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San Fernando, B1646EBJ, Argentina
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San Juan Bautista, 1888, Argentina
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Coffs Harbour, 02450, Australia
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Frankston, 3199, Australia
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Garran, 2605, Australia
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Nedlands, 6009, Australia
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New Lambton, 2310, Australia
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Spearwood, 6163, Australia
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Wollongong, 2500, Australia
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Woodville South, 5011, Australia
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Genk, 3600, Belgium
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Ghent, 9000, Belgium
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Jette, 1090, Belgium
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Leuven, 3000, Belgium
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Mechelen, 2800, Belgium
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Namur, 5101, Belgium
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Dupnitsa, 2600, Bulgaria
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Haskovo, 6300, Bulgaria
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Lovech, 5500, Bulgaria
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Pleven, 5804, Bulgaria
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Plovdiv, 4003, Bulgaria
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Rousse, 7000, Bulgaria
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Rousse, 7000, Bulgaria
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Sofia, 1000, Bulgaria
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Sofia, 1202, Bulgaria
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Sofia, 1431, Bulgaria
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Sofia, 1756, Bulgaria
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Stara Zagora, 6003, Bulgaria
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Varna, 9000, Bulgaria
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Veliko Tanovo, 5000, Bulgaria
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Veliko Tarnovo, 5000, Bulgaria
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Vidin, 3700, Bulgaria
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Yambol, 8600, Bulgaria
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NOT_YET_RECRUITING

Armenia, 630004, Colombia
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NOT_YET_RECRUITING

Barranquilla, 080020, Colombia
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NOT_YET_RECRUITING

Bogotá, 110131, Colombia
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Cali, 760042, Colombia
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Ibagué, 730006, Colombia
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Manizales, 170004, Colombia
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Medellín, 050022, Colombia
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Medellín, 050030, Colombia
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Aalborg, 9000, Denmark
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Hvidovre, 2650, Denmark
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Næstved, 4700, Denmark
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Odense C, 5000, Denmark
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Vejle, 7100, Denmark
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Brest, 29609, France
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Lyon, 69317, France
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Marseille, 13915, France
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Montpellier, 34295, France
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Paris, 75014, France
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Paris, 75877, France
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Pessac, 33604, France
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Saint-Herblain, 44800, France
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Athens, 11521, Greece
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Athens, 11527, Greece
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Athens, 17562, Greece
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Heraklion, 71110, Greece
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Ioannina, 45500, Greece
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Pátrai, 26332, Greece
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Thessaloniki, 57001, Greece
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Thessaloniki, 57010, Greece
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Hong Kong, 999077, Hong Kong
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Hong Kong, Hong Kong
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Budapest, 1036, Hungary
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Debrecen, 4032, Hungary
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Edelény, 3780, Hungary
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Gödöllő, 2100, Hungary
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Hatvan, 3000, Hungary
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Mosonmagyaróvár, 9200, Hungary
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Nyíregyháza-Sóstóhegy, 4481, Hungary
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Törökbálint, 2045, Hungary
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Ashkelon, 78278, Israel
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Haifa, 34362, Israel
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Jerusalem, 00000, Israel
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Jerusalem, 90131, Israel
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Kfar Saba, 4428164, Israel
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Ramat Gan, 52621, Israel
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Rehovot, 76100, Israel
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Tel Aviv, 6423906, Israel
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Akashi-shi, 674-0063, Japan
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Chikushino-shi, 818-8502, Japan
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Chiyoda-ku, 1020074, Japan
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Fukui-shi, 910-8526, Japan
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Fukuoka, 811-1394, Japan
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Fukuoka, 819-8555, Japan
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Gifu, 502-8558, Japan
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Iruma-Gun, 350-0495, Japan
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Ishinomaki, 986-8522, Japan
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Kasuga-shi, 816-0864, Japan
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Kitakyushu-shi, 807-8555, Japan
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Kiyose-shi, 204-8522, Japan
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Kiyose-shi, 204-8585, Japan
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Kobe, 650-0047, Japan
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Komatsu-shi, 923-8560, Japan
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Kure-shi, 737-8505, Japan
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Kyoto, 612-8555, Japan
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Matsusaka-shi, 515-8544, Japan
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WITHDRAWN

Meguro-ku, 153-0051, Japan
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Minatoku, 105-8470, Japan
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Minatoku, 108-0073, Japan
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Miyazaki, 889-1692, Japan
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Mizunami-shi, 509-6134, Japan
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Nagaoka-shi, 940-8621, Japan
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Nagasaki, 852-8501, Japan
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Nagoya, 457-0866, Japan
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Nagoya, 457-8511, Japan
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Nagoya, 466-8650, Japan
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Nerima-ku, 177-8521, Japan
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Ohta-ku, 143-0013, Japan
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Okayama, 700-8558, Japan
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Okayama, 701-1192, Japan
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Osaka, 540-0008, Japan
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Sapporo, 064-0804, Japan
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Sendai, 980-8574, Japan
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Sendai, 983-8520, Japan
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Shinjuku-ku, 160-8582, Japan
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Shinjuku-ku, 162-8655, Japan
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Shinjuku-ku, 162-8666, Japan
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Shiogama, 985-8506, Japan
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Takamatsu, 760-0018, Japan
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Takatsuiki-shi, 569-1096, Japan
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Tanabe-shi, 646-8558, Japan
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Toshima-ku, 171-0014, Japan
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Ube, 755-8505, Japan
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Yokohama, 236-0004, Japan
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Yokohama, 245-8575, Japan
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Eindhoven, 5623 EJ, Netherlands
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NOT_YET_RECRUITING

Maastricht, 6229 HX, Netherlands
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Rotterdam, 3045 PM, Netherlands
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Rotterdam, 3083 AN, Netherlands
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Zutphen, 7207 AE, Netherlands
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Auckland, 0626, New Zealand
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Auckland, 1051, New Zealand
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Auckland, 2025, New Zealand
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Hamilton West, 3204, New Zealand
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Tauranga, 3112, New Zealand
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NOT_YET_RECRUITING

Cusco, CUSCO 01, Peru
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NOT_YET_RECRUITING

Lima, 15036, Peru
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Lima, 15046, Peru
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NOT_YET_RECRUITING

Lima, 15088, Peru
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NOT_YET_RECRUITING

Lima, LIMA 01, Peru
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Lima, LIMA 1, Peru
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Lima, LIMA 21, Peru
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Lima, LIMA 33, Peru
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NOT_YET_RECRUITING

Piura, 20001, Peru
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WITHDRAWN

Bucharest, 011461, Romania
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Bucharest, 050159, Romania
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Cluj-Napoca, 400275, Romania
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Cluj-Napoca, 400332, Romania
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Oradea, 410176, Romania
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Timișoara, 300002, Romania
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Timișoara, 300310, Romania
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Benoni, 1501, South Africa
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Cape Town, 7700, South Africa
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Durban, 4001, South Africa
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Durban, 4093, South Africa
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eMkhomazi, 4170, South Africa
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Kimberley, 8301, South Africa
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Somerset West, 7130, South Africa
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Tygervalley, 7530, South Africa
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Gothenburg, 413 46, Sweden
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Karlskrona, 371 79, Sweden
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Lund, 22185, Sweden
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Örebro, 703 62, Sweden
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Stockholm, 11446, Sweden
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Stockholm, 171 64, Sweden
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Bang Kra So, 11000, Thailand
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Bangkok, 10330, Thailand
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Hat Yai, 90110, Thailand
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Muang, 22000, Thailand
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Muang, 40002, Thailand
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Mueang, 20000, Thailand
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Rayong, 21000, Thailand
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Adana, 1330, Turkey (Türkiye)
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Ankara, 6620, Turkey (Türkiye)
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Istanbul, 34020, Turkey (Türkiye)
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Kayseri, 38039, Turkey (Türkiye)
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Kocaeli, 41380, Turkey (Türkiye)
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Mersin, 33079, Turkey (Türkiye)
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Da Nang, 550000, Vietnam
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Haiphong, 180000, Vietnam
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Hanoi, 100000, Vietnam
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Ho Chi Minh City, 700000, Vietnam
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NOT_YET_RECRUITING

Ho Chi Minh City, 700000, Vietnam
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NOT_YET_RECRUITING

Ho Chi Minh City, Vietnam
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RECRUITING

Hồ Chí Minh, 700000, Vietnam
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Huế, 530000, Vietnam

Conditions

Explore the condition pages connected to this study.

CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD)