First human tests begin for experimental drug TEV-56286

NCT ID NCT07674940

First seen Jun 30, 2026 · Last updated Jul 01, 2026 · Updated 1 time

Summary

This early-stage trial tests the safety and how the body handles TEV-56286 (also known as emrusolmin or anle138b) in healthy adults. Participants receive either single or multiple rising doses of the drug or a placebo. The study measures how the drug is absorbed, distributed, and eliminated, and monitors for any side effects. Results will help determine safe doses for future studies in people with diseases.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

TEV-56286 (emrusolmin, anle138b)

What this could lead to

If safe and well-tolerated, this could pave the way for future studies testing TEV-56286 as a treatment for diseases like Parkinson's or other protein-aggregation disorders.

What could go wrong

This is an early, first-in-human trial in healthy volunteers, so it cannot show whether the drug works for any disease. Side effects or poor tolerability may stop further development.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

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