RA treatment showdown: low activity vs. remission
NCT ID NCT06046950
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study compares two treatment strategies for rheumatoid arthritis (RA): aiming for low disease activity versus aiming for remission. 340 adults with RA who are starting or already on disease-modifying drugs will be randomly assigned to one of these targets. The goal is to see which approach leads to better control of joint damage and symptoms over 18 months.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Treatment strategy (treat-to-target with DAS28CRP-LDA or SDAI-remission)
What this could lead to
If successful, this study could show which treatment target (low disease activity or remission) is more effective and cost-effective for managing rheumatoid arthritis.
What could go wrong
This is a strategy trial, not testing a new drug. Results may not apply to all patients, and the more stringent remission target may be harder to achieve or cause more side effects.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Sint Maartenskliniek
Ubbergen, 6574 NA, Netherlands