New hope for controlling rare genetic tumors

NCT ID NCT04374305

Summary

This study is testing two repurposed cancer drugs, brigatinib and neratinib, to see if they can slow or stop the growth of tumors in people with NF2-related schwannomatosis. It will enroll about 100 participants aged 12 and older who have specific, growing tumors. The trial uses a flexible 'basket' design, allowing participants to potentially try different treatments if their first one stops working.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Indiana University School of Medicine

    Indianapolis, Indiana, 46202, United States

  • Johns Hopkins Hospital

    Baltimore, Maryland, 21287, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, 02115, United States

  • New York University Langone Medical Center

    New York, New York, 10016, United States

  • UCLA Medical Center

    Los Angeles, California, 90095, United States

  • University of Miami

    Miami, Florida, 33136, United States

Conditions

Explore the condition pages connected to this study.