Could a $4 blood pressure pill boost brain energy in Parkinson's?
NCT ID NCT07464028
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This Phase 2 trial tests whether terazosin, a drug already used for high blood pressure, can improve energy production in the brains of people with Parkinson's disease. Researchers will measure changes in a key energy molecule (ATP) in 120 participants over 1.5 years. If it works, it could lead to a new approach to slow the disease.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Terazosin (a drug that may boost energy production in cells)
- What this could lead to
- If successful, this could point toward a new way to slow Parkinson's progression by improving how brain cells produce energy.
- What could go wrong
- This is an early Phase 2 trial with only 120 people. It tests a biological marker (ATP), not yet whether patients feel better. The drug may not show clear benefits or could have side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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