Could a $4 blood pressure pill boost brain energy in Parkinson's?

NCT ID NCT07464028

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This Phase 2 trial tests whether terazosin, a drug already used for high blood pressure, can improve energy production in the brains of people with Parkinson's disease. Researchers will measure changes in a key energy molecule (ATP) in 120 participants over 1.5 years. If it works, it could lead to a new approach to slow the disease.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Terazosin (a drug that may boost energy production in cells)

What this could lead to

If successful, this could point toward a new way to slow Parkinson's progression by improving how brain cells produce energy.

What could go wrong

This is an early Phase 2 trial with only 120 people. It tests a biological marker (ATP), not yet whether patients feel better. The drug may not show clear benefits or could have side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Parkinson disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••