500 cancer patients join quest to unlock hidden clues in their blood and tumors

NCT ID NCT06163534

Recruiting now Knowledge-focused Sponsor: Tempus AI Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study enrolls 500 adults with advanced head and neck cancer who are starting standard immunotherapy. Researchers will collect blood and tumor samples over time to look for genetic and immune markers that may predict how well treatment works or why it stops working. The goal is to gather information to improve future treatments, not to test a new drug.

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Conditions

The condition(s) this trial relates to.

head and neck squamous cell carcinoma neoplasm Squamous Cell Carcinoma of Head and Neck

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEAD AND NECK SQUAMOUS CELL CARCINOMA

Contacts and locations

Locations

Cancer Care Associates of York
RECRUITING

York, Pennsylvania, 17403, United States
Cancer Care Specialists of Illinois
RECRUITING

Decatur, Illinois, 62526, United States
City of Hope
RECRUITING

Duarte, California, 91010, United States
Cleveland Clinic
RECRUITING

Cleveland, Ohio, 44195, United States
Dana Farber Cancer Institute
RECRUITING

Boston, Massachusetts, 02215, United States
Henry Ford
RECRUITING

Detriot, Michigan, 48202, United States
Illinois Cancer Care
RECRUITING

Peoria, Illinois, 61615, United States
Karmanos Cancer Institute
RECRUITING

Detroit, Michigan, 48201, United States
Morehouse
RECRUITING

Atlanta, Georgia, 30310, United States
Mount Sinai Hospital
RECRUITING

New York, New York, 10029, United States
Northwestern University Feinberg School of Medicine
RECRUITING

Chicago, Illinois, 60611, United States
Ohio State University
RECRUITING

Columbus, Ohio, 43210, United States
Oncology Hematology Associates
RECRUITING

Springfield, Missouri, 65807, United States
Pan American Cancer for Oncology
ACTIVE_NOT_RECRUITING

San Juan, 00909, Puerto Rico
Piedmont Healthcare
RECRUITING

Atlanta, Georgia, 30318, United States
Providence Medical Foundation
RECRUITING

Santa Rosa, California, 95403, United States
Sanford Fargo
RECRUITING

Fargo, North Dakota, 58102, United States
Sanford Sioux Falls
RECRUITING

Sioux Falls, South Dakota, 57104, United States
Stanford
RECRUITING

Palo Alto, California, 94304, United States
ThedaCare
RECRUITING

Appleton, Wisconsin, 54911, United States
USC/Norris Comprehensive Cancer Center
RECRUITING

Los Angeles, California, 90033, United States
University of California, Los Angeles
RECRUITING

Los Angeles, California, 90095, United States
University of Cincinnati
RECRUITING

Cincinnati, Ohio, 45219, United States
University of Kansas
RECRUITING

Westwood, Kansas, 66205, United States
University of Maryland
RECRUITING

Baltimore, Maryland, 21202, United States
University of Pennsylvania
RECRUITING

Philadelphia, Pennsylvania, 19104, United States
University of Washington
RECRUITING

Seattle, Washington, 98109, United States
Vanderbilt University
RECRUITING

Nashville, Tennessee, 37212, United States
Washington University in St. Louis
RECRUITING

St Louis, Missouri, 63130, United States
Winship Cancer Institute, Emory University
RECRUITING

Atlanta, Georgia, 30322, United States

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