Gene therapy takes on deadly brain tumor

NCT ID NCT03866109

Terminated Disease control Sponsor: Genenta Science Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new treatment called Temferon for people with glioblastoma, a fast-growing brain cancer. The therapy uses a patient's own blood stem cells, modified to deliver interferon directly to the tumor. Up to 27 patients with a specific genetic marker (unmethylated MGMT) will receive a single injection after standard treatment to see if it is safe and helps control the disease.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for GLIOBLASTOMA MULTIFORME are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

glioblastoma glioma susceptibility 1

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GLIOBLASTOMA MULTIFORME

Contacts and locations

Locations

Fondazione IRCCS Istituto Neurologico "Carlo Besta"

Milan, 20133, Italy
Ospedale San Raffaele

Milan, 20132, Italy
Policlinico Universitario Fondazione Agostino Gemelli

Rome, Italy

More trials for these conditions

Other studies related to the condition(s) this trial covers.