Gene therapy takes on glioblastoma: new hope for aggressive brain cancer?
NCT ID NCT03866109
First seen Feb 09, 2026 · Last updated May 14, 2026 · Updated 12 times
Summary
This early-phase trial tests a new treatment called Temferon for glioblastoma, a fast-growing brain cancer. It uses a patient's own blood stem cells, modified to deliver an immune-boosting protein (interferon) directly to the tumor. The study enrolls up to 27 people whose tumors have a specific genetic marker (unmethylated MGMT) and aims to find a safe dose while checking for side effects.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Fondazione IRCCS Istituto Neurologico "Carlo Besta"
Milan, 20133, Italy
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Ospedale San Raffaele
Milan, 20132, Italy
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Policlinico Universitario Fondazione Agostino Gemelli
Rome, Italy
Conditions
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