Promising combo targets early triple-negative breast cancer

NCT ID NCT06604858

First seen Dec 24, 2025 · Last updated May 16, 2026 · Updated 20 times

Summary

This study tests whether adding the immunotherapy drug pembrolizumab to standard chemotherapy (carboplatin and paclitaxel) can completely eliminate tumors in people with stage I triple-negative breast cancer before surgery. About 31 participants with small, lymph-node-negative tumors will receive the combination, then have surgery to check for any remaining cancer. The main goal is to see how many achieve a complete response, meaning no cancer is found in the breast or lymph nodes.

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Contacts and locations

Locations

  • Complejo Hospitalario Universitario A Coruña (CHUAC)

    A Coruña, Spain

  • Complejo Hospitalario Universitario de Santiago (CHUS)

    Santiago de Compostela, Spain

  • Hospital Arnau de Vilanova de Valencia

    Valencia, Spain

  • Hospital Beata María Ana

    Madrid, Spain

  • Hospital Cínico San Carlos

    Madrid, Spain

  • Hospital Universitari Dexeus

    Barcelona, Spain

  • Hospital Universitari Vall D'Hebron

    Barcelona, Spain

  • Hospital Universitario Clínico San Cecilio de Granada

    Granada, Spain

  • Hospital Universitario Virgen del Rocío

    Seville, Spain

  • Hospital Universitario de Navarra

    Pamplona, Spain

  • Institut Català d' Oncologia Girona (ICO)

    Girona, Spain

Conditions

Explore the condition pages connected to this study.