New Two-Drug combo shows promise against stomach bug

NCT ID NCT06950489

Completed Disease control Sponsor: Soonchunhyang University Hospital Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a two-drug combination—tegoprazan (a stomach acid blocker) and amoxicillin (an antibiotic)—to treat H. pylori infection, a common stomach bug that can cause ulcers. The trial enrolled 50 adults who had not been treated for H. pylori before. The goal was to see if this simpler regimen could effectively clear the infection with fewer side effects than standard three- or four-drug treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: tegoprazan and amoxicillin
What this could lead to: If successful, this could offer a simpler, well-tolerated treatment option for H. pylori infection, especially when other antibiotics don't work.
What could go wrong: This is a small, early feasibility study with only 50 participants. It may not prove the treatment works better than existing options, and results may not apply to everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for H.PYLORI INFECTION are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Helicobacter pylori infectious disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

H.PYLORI INFECTION

Contacts and locations

Locations

Digestive Disease Center, Soonchunhyang University Hospital

Seoul, 04401, South Korea

More trials for these conditions

Other studies related to the condition(s) this trial covers.