Can a phone app explain why depression hits girls harder in puberty?
NCT ID NCT06072677
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at how sex hormones during puberty might affect mood differently in boys and girls. Researchers are testing a 4-week smartphone training program called Healthy Minds Program in 60 adolescents aged 11-14. The goal is to understand the brain and hormone changes that could explain why depression rates rise more in girls during this time.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Healthy Minds Program (smartphone-based training)
What this could lead to
If successful, this could reveal why depression rates differ between boys and girls during puberty, pointing toward sex-specific prevention strategies.
What could go wrong
This is a small, early-stage study (60 participants) focused on understanding mechanisms, not testing a treatment. Results may not apply to all teens.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for ADOLESCENT DEPRESSION are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
Carolina Crossing B, Suite 1
RECRUITINGChapel Hill, North Carolina, 27517, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••